MicroRNAs in skeletogenesis
نویسندگان
چکیده
منابع مشابه
MicroRNAs in skeletogenesis.
MicroRNAs (miRNAs) are a class of highly conserved small noncoding RNAs that negatively regulate gene expression by imperfectly base pairing to the 3'-untranslated region of their target mRNAs, leading to mRNA degradation or translational inhibition. The emerging field of miRNA biology has begun to unravel roles for these regulatory molecules in a variety of biological processes. This review co...
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Members of the Wnt gene family, encoding secreted cystein-rich glycoproteins, have been isolated from a variety of organisms. They serve as important developmental signaling molecules and have been implicated to play crucial roles in such diverse processes as cancer, organogenesis and pattern formation. Experiments by Zakany and Duboule, and Rudnicki and Brown have suggested a role for Wnt mole...
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ژورنال
عنوان ژورنال: Frontiers in Bioscience
سال: 2009
ISSN: 1093-9946,1093-4715
DOI: 10.2741/3412